Anthelmintic-based taste aversions in wolves

The use of lithium chloride (LiCl) as an oral illness-producing agent in taste aversion studies has been questioned. Because of the detectability of LiCl, a different aversion-producing substance may be needed. To test the anthelmintic thiabendazole (TBZ) as an aversion-producing agent, 5 wolves (Canis lupus) were tested with 4 different foods. For each test, 2 wolves were given treated food and 3 were used as controls. A different pair of wolves were treated with each food. One wolf did not receive any treated food, while each of the other 4 wolves received treatments with 2 different foods. Treatment consisted of mixing 500 g of food with 2 g of TBZ. Of the 4 times wolves were treated, one, using chicken franks, produced no apparent aversions. Reductions in consumptions for the remaining 3 foods were 29% with spaghettios, 75% with dog food, and 100% with turkey soup.

Author J. M. Ziegler, C. R. Gustavson, G. A. Holzer and D. Gruber
Year 1982
Volume 9
Pages 373-377